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A cell-permeable compound that prevents various bacterial toxins from exerting their cytotoxic activity by blocking endosomal trafficking/maturation into acidified late endosomes.
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Highly pure fluorescent exosome standards with superior performance, suitable for extracellular vesicle (EV) tracking studies, flow cytometry, and electron microscopy
Thermo Scientific™ CaptureSelect™ HRP Anti-AAV9 Conjugate includes a 13-kDa recombinant single domain antibody fragment (VHH affinity ligand) that specifically binds adeno-associated virus particles of serotype 9 (AAV9).
CFTR Inhibitor II, GlyH-101, CAS 328541-79-3, is a cell-permeable potent, selective and reversible open-channel blocker of CFTR (Ki = 4.3 μM in CFTR-expressing FRT cells).
A cell-permeable purine compound that binds ARFGAPs (Kd = 364 and 620 nM for AMAP1 and ARFGAP1, respectively) and acts as a broad specificity ARFGAPs inhibitor (GTPase activating proteins of ADP-ribosylation factor).
The Caspase-1 Inhibitor I, also referenced under CAS 143313-51-3, controls the biological activity of Caspase-1. This small molecule/inhibitor is primarily used for Cancer applications.
A cell-permeable, reversible, substrate competitive, and specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor tyrosine kinase activity.
A selective, competitive antagonist of GABAA receptor (IC50 = 440nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (∽1